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What is a proteoform?

“Proteoform” is protein identity + site-specific modifications, which
DNA can’t predict.

One protein can have dozens of proteoforms,
making peptide proteomics a guessing game.

  • Truncation

  • Phosphorylation

  • Glycosylation

  • Ubiquitination

  • Methylation

  • Acetylation

  • Lipidation

This J Proteome Res Paper explains how understanding proteoforms with peptides is impossible.
Read up on our technology

Examples of Problems We Solve With Proteoforms

  • I can’t find a good biomarker

  • I can’t figure out where truncation happens

  • I can’t identify or localize co-occurring modifications

  • I can’t prove that I’m expressing the right thing

  • I can’t aggregate my project data into a scalable database

  • I can’t solve the “garbage in/garbage out” problem of my AI proteomics stack

Want to unlock the power of proteoforms?

We are excited to work with you on your next project!